Fig. 2.
The influence of PP2 on the ouabain-sensitive 86Rb uptake response to 8-Br-cGMP. Cells were cultured to confluence on permeable inserts and pre-incubated with PP2 (10 μM) for 40 min before being exposed to 8-Br-cGMP (100 μM) in the continued presence of PP2. 8-Br-cGMP was introduced for 5 min and then 86RbCl ± ouabain (500 μM) was added for a further 5 min in the continued presence of 8-Br-cGMP. The values are the mean ± SEM of results from four cell monolayers. ***Indicates a significant difference from control, P < 0.001.