Individual differences in daily energy metabolism during circadian misalignment in study 2. A) Change in 24 h energy expenditure from baseline during circadian misalignment, B) 24 h respiratory quotient (RQ), C) energy expenditure during scheduled wake, D) change in scheduled sleep energy expenditure from baseline during circadian misalignment. Grey squares represent average data for study day 2 (baseline) with scheduled wake during the daytime and sleep at night, red circles represent data for study day 4 with scheduled sleep during the daytime and wake at night (night shift 2), blue triangles represent data for study day 5 with scheduled sleep during the daytime and wake at night (night shift 3). Data for the 14 individual subjects are displayed along the x-axis plotted according to the rank order of subjects’ change in 24 h energy expenditure shown in 7A. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)