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. 2018 Jun 4;13(6):e0197176. doi: 10.1371/journal.pone.0197176

Fig 8. Evaluation of the quaternary structure annotation of PDB entry 1Z77.

Fig 8

All methods (SC: sequence clustering, TM: text mining, PISA, EPPIC) are selected for the evaluation process. The output includes two parts: oligomeric state and symmetry. In the oligomeric state table, it states that 1Z77 (first column: PDB ID) has one oligomeric state prediction (second column: BA Number), and it is annotated as a monomeric structure in the PDB (third column: PDB). However, according to SC (fourth column: Sequence clustering), PISA (fifth column), EPPIC (sixth column), and TM (seventh column: Text Mining), 1Z77 is a dimeric protein. Therefore, our consensus result (eighth column) states that 1Z77 is a dimer. In the symmetry table one quaternary structure prediction is shown (second column: BA Number), having C1 symmetry (third column: PDB). However, according to SC (fourth columns: Sequence cluster), PISA (fifth column) and EPPIC (sixth column), 1Z77 has a C2 symmetry. Therefore our consensus result (seventh column) states that 1Z77 has a C2 symmetry. Red denotes divergence between current PDB annotation of oligomeric state and results provided by each of the four evaluation methods.