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. 2018 Apr 17;293(22):8315–8329. doi: 10.1074/jbc.RA118.002297

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© 2018 Sun et al.

Published under exclusive license by The American Society for Biochemistry and Molecular Biology, Inc.

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Figure 6. — Reconstruction of the mammary epithelial developmental trajectory. A, single cells from virgin and P12 mice could be further divided into five (left panel) and six (right panel) subgroups with separate distinct markers. LBLCs is short for lipid biosynthetic luminal cells; KLCs is short for keratinized luminal cells; SRLCs is short for stimulus-responsive luminal cells; PBCs is short for proliferative basal cells; WRBCs is short for Wnt signaling–responsive basal cells; Mature LCs is short for mature luminal cells; and PLCs is short for proliferative luminal cells. B, Monocle analysis reconstructs the differentiation trajectory of mouse MaSCs in virgin and P12 mice (top), and the pseudo-differentiation trajectory of MaSCs are shown at bottom.