Table 3.
Statistically significant changes in abundance of proteins involved in cell division.
| Cell Proliferation/Carcinogenic proteins |
P-value by exposure duration (min) |
|||
|---|---|---|---|---|
| Protein endpoint | 2 | 15 | 60 | 240 |
| pc-Abl | 0.00286 ↑ | 0.00114 ↑ | ||
| pMDM2 S166 | 0.00970 ↑ | |||
| pMetY1234/1235 | 0.03248 ↑ | |||
| NUMB | 0.00356 ↑ | |||
| pPLK1 T210 | 0.04029 ↑ | |||
| p53 | 0.00397 ↑ | |||
A two-tailed unpaired heteroscedastic t-test was performed to determine whether PMA caused statistically significant change (p < 0.05) in the abundance of proteins and phosphoproteins related to cell proliferation and/or implicated in carcinogenesis. Arrows indicate increases or decreases in endpoint abundance.