We suggest the following schedules for vitamin D supplementation: Deficiency and insufficiency: 50,000 IU once a week for 8 weeks; alternatively, a daily dose of 5000 IU for 8 weeks; Maintenance of sufficiency: 50,000 IU twice a month; alternatively, a daily dose of 2000 IU. We suggest an individually tailored approach for vitamin D administration, involving the patient‘s opinion about the schedule (daily, weekly or monthly) that may offer the best adherence.