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. 2018 May 7;10(5):573. doi: 10.3390/nu10050573

Table 5.

Evolution of symptoms of non-coeliac gluten sensitivity after 1 year of a GFD.

Parameters Pre-GFD Post-GFD p
Upper respiratory tract infections, (X ± SD), (Maximum 18)
  -Children 3.2 ± 2.1 0.6 ± 0.9 =0.000
  -Adults 4.5 ± 4.9 0.2 ± 0.4 =0.680
Lower respiratory tract infections, (X ± SD), (Maximum 9)
  -Children 2.1 ± 2.2 0.1 ± 0.4 =0.001
  -Adults 1.3 ± 2.1 0.3 ± 0.8 =0.180
Associated allergies, (X ± SD), (Maximum 27)
  -Children 1.8 ± 3.4 1.7 ± 2.4 =0.782
  -Adults 1.3 ± 2.8 2.2 ± 3.7 =0.285
Headaches and/or migraines, (X ± SD), (Maximum 18)
  -Children 1.7 ± 2.7 0.4 ± 0.6 =0.013
  -Adults 4.8 ± 4.9 0.8 ± 1.2 =0.068
Infectious oral processes, (X ± SD), (Maximum 15)
  -Children 3.0 ± 2.3 1.0 ± 1.3 =0.000
  -Adults 3.8 ± 4.2 0.5 ± 0.8 =0.104
Other dental changes, (X ± SD), (Maximum 15)
  -Children 2.1 ± 1.6 1.6 ± 1.3 =0.105
  -Adults 2.8 ± 2.1 1.8 ± 1.0 =0.276
Musculoskeletal affectation, (X ± SD), (Maximum 36)
  -Children 5.0 ± 5.7 1.4 ± 2.5 =0.002
  -Adults 9.0 ± 12.7 1.3 ± 2.0 =0.042
Dermatitis, (X ± SD), (Maximum 45)
  -Children 4.8 ± 6.3 1.4 ± 1.9 =0.002
  -Adults 6.3 ± 4.9 2.0 ± 2.1 =0.058
Anaemia and/or ferropaenia, (X ± SD), (Maximum 24)
  -Children 2.8 ± 3.1 0.8 ± 1.4 =0.004
  -Adults 4.0 ± 3.6 1.2 ± 1.5 =0.131
Sleep disorders, (X ± SD), (Maximum 27)
  -Children 6.2 ± 6.4 1.6 ± 2.0 =0.000
  -Adults 8.7 ± 5.3 2.0 ± 1.3 =0.046
Behavioural disorders, (X ± SD), (Maximum 24)
  -Children 7.2 ± 5.6 2.6 ± 4.1 =0.002
  -Adults 16.0 ± 3.0 3.0 ± 4.5 =0.028
Urinary disorders, (X ± SD), (Maximum 21)
  -Children 1.8 ± 2.7 0.7 ± 1.3 =0.082
  -Adults 3.3 ± 5.3 0.5 ± 0.8 =0.109
Dietary disorders, (X ± SD), (Maximum 45)
  -Children 9.5 ± 9.5 1.3 ± 1.9 =0.000
  -Adults 10.5 ± 9.4 1.8 ± 1.2 =0.027
Change in intestinal habit, (X ± SD), (Maximum 33)
  -Children 9.1 ± 6.8 3.7 ± 4.8 =0.001
  -Adults 7.7 ± 5.2 2.3 ± 2.1 =0.075

The tests used were the Wilcoxon signed-rank test for adults, the Student paired test for children and the McNemar test for drugs consumption. GFD = Gluten-free diet; X = Mean; SD = Standard Deviation.