Table 3.
The effects of dietary sugar on hs(CRP).
| hs(CRP) (mg/L) Intervention vs. Control | No. of Studies | No. of Participants | MD | 95% CI | p-Value | I2 (%) (95% CI) 1 | Quality of Meta-Evidence (NutriGrade) 2 |
|---|---|---|---|---|---|---|---|
| Fructose vs glucose | 6 | 403 | −0.03 | −0.52, 0.46 | (p = 0.90) | 44 (0, 75) | Low |
| HFCS vs sucrose | 3 | 677 | 0.21 | −0.11, 0.53 | (p = 0.19) | 0 (0, 75) | Low |
HFCS, high-fructose corn syrup. Pooled estimates of effect sizes (95% confidence intervals) expressed as mean differences (MD). MD = mean of intervention group—mean of control group. MD = 0: no difference between groups. MD > 0: greater value of respective outcome measured in intervention (first) groups. MD < 0: greater value of respective outcome measured in control (second) groups. 1 I2 value represents degree of heterogeneity within comparison groups. I2-value of greater than 50% was considered to indicate substantial heterogeneity. 2 Nutrigrade is an applied scoring system to judge the quality of meta-evidence [22].