. 2018 May 4;14:140–148. doi: 10.1016/j.bbrep.2018.04.009

Table 2.

Various proteomic studies conducted on probiotics, revised after [86].

Topic	Separation and detection methods	Identification methods	Potentially probiotic strains	Reference
Basic proteome research
Proteome catalogue	No data	NanoLC-MS/MS, MALDI-MS/MS, CXC-LC-MS/MS	P. freudenreichii CIRM-BIA1,	Falentin et a l., 2010 [87]
Proteome catalogue and comparison of strains	SDS-PAGE	NanoLC-MS/MS	L. rhamnosus GG and Lc705	Savijoki et al., 2011 [88]
Proteome map, growth on lactitol	2-D GE, Coomassie staining,2-D DIGE	MALDI-MS/	L. acidophilus NCFM	Majumder et al., 2011 [89]
Proteome map, growth on lactitol	2-D GE, Coomassie staining,2-D DIGE	MS	L. acidophilus NCFM	Majumder et al., 2011 [89]
Comparison of Strains and Growth Phases
Comparison of strains	2-D GE, Coomassie staining	MALDI-MS	B. longum NCC2705	Aires et al., 2010 [90]
Comparison of strains and growth on different media	2-D GE, SYPRO Ruby staining	LC-MS/MS	L. rhamnosus E-97800	Plumed-Ferrer et al., 2008 [91]
Comparison of strains and growth on different media	2-D GE, SYPRO Ruby staining	LC-MS/MS	L. plantarum MLBPL1	Plumed-Ferrer et al., 2008 [91]
Stress
Bile stress	2-D GE, Coomassie staining	MALDI-MS	L. delbrueckii subsp.lactis 200 L. plantarum 299 V	Burns et al., 2010 [92]
Bile stress	2-D GE, Coomassie staining	LC-MS/MS	B. animalis subsp. Lactis B107	Hamon et al., 2011 [93]
Effect of bile stress on cell wall proteome	2-D GE, silver staining	MALDI-MS		Candela et al.,2010 [94]
Acid stress	2-D GE, silver staining	MALDI-MS	L. casei Zhang	Wu et al., 2011 [95]
Acid stress	2-D GE, silver staining	MALDI-MS	L. reuteri ATCC 23272	Lee and pi, 2010 [96]
Oxidative stress	2-D GE, Coomassie staining	MALDI-MS	B. longum subsp.longum BBMN68	Xiao et al., 2011 [97]
Comparison of strains with different stress tolerance	LC	LC-MS/MS	B. longum NCC2705	Guillaume et al., 2009 [98]