Table 3  Breast cancer risk assessment tools.

Risk Factor, Reference	NCI model 111 ,  112	Claus model 113	Tyrer-Cuzick model 65 ,  79 ,  114 ,  115	BRCAPRO 67 ,  73	BOADICEA 66 ,  71 ,  72	Tice 116	Darabi 117	Eriksson 118
Abbreviations: NCI: National Cancer Institute; BOADICEA: Breast and Ovarian Analysis of Disease Incidence and Carrier Estimation Algorithm.
Age	+	+	+	+	+	+	+	+
Age at menarche	+		+				+
Age at menopause			+					+
Body mass index			+				+	+
Age at first birth	+		+				+
Mammographic density			+			+	+	+
Suspicious mammographic findings								+
History of breast biopsies	+		+			+	+
History of premalignant lesions	+		+				+
Hormone replacement therapy			+					+
Family history of breast cancer	+	+	+	+	+		+	+
Family history of ovarian cancer			+	+	+
Family history of prostate cancer					+
Family history of pancreatic cancer					+
Contralateral breast cancer			+	+	+
Histology of breast cancer				+	+
BRCA1/2 mutation	+		+	+	+
Low penetrant genetic variants			(+)				+
Ethnicity/Ashkenazi Jewish ancestry	+		+	+	+	+	+
Mastectomy				+
Oophorectomy				+