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. Author manuscript; available in PMC: 2019 Aug 1.
Published in final edited form as: Shock. 2018 Aug;50(2):141–148. doi: 10.1097/SHK.0000000000001074

Table 2.

Mixed multiple regression models for mitochondrial respiratory states based on 97 biopsies obtained from 55 pediatric burn patients

Mitochondrial respiratory states in pmol·s−1·mg−1
Predictors Leak (State 2) State 3I Max State 3I+II State 4O
Beta (95% CI) P Beta (95% CI) P Beta (95% CI) P Beta (95% CI) P
(Intercept) 14.64 (11.67, 17.60) <0.0001 29.98 (23.22, 36.75) <0.0001 35.83 (27.49, 44.17) <0.0001 13.81 (10.67, 16.94) <0.0001
Age 0.11 (−0.10, 0.31) 0.310 −0.22 (−0.70, 0.26) 0.373 −0.05 (−0.64, 0.53) 0.855 0.07 (−0.15, 0.29) 0.524
Sex
  Females −0.08 (−2.46, 2.30) 0.946 −7.12 (−12.59, −1.65) 0.015 −5.50 (−12.22, 1.22) 0.117 0.94 (−1.60, 3.48) 0.471
  Males Ref Ref Ref Ref Ref Ref Ref Ref
Sepsis
  Positive −3.20 (−5.93, −0.47) 0.027 −6.87 (−13.01, −0.73) 0.034 −7.16 (−14.78, 0.47) 0.073 0.54 (−2.30, 3.37) 0.711
  Negative Ref Ref Ref Ref Ref Ref Ref Ref
TBSA-3rd 0.03 (−0.03, 0.08) 0.377 0.15 (0.02, 0.28) 0.031 0.28 (0.12, 0.44) 0.002 0.05 (−0.02, 0.11) 0.148
A2S −0.10 (−0.23, 0.02) 0.115 −0.17 (−0.44, 0.09) 0.208 −0.35 (−0.69, −0.01) 0.049 −0.10 (−0.22, 0.03) 0.130

Ref, male sex was used as a reference category in the regression models; TBSA-3rd, percent total body surface area with full-thickness burns; A2S, time from admission to study