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. Author manuscript; available in PMC: 2019 Jun 1.
Published in final edited form as: Semin Cancer Biol. 2018 Jan 5;50:65–76. doi: 10.1016/j.semcancer.2018.01.004

Figure 1. FoxO regulation by growth factor and stress signaling.

Figure 1

Growth factors inhibit FoxOs whereas stress signaling generally activates FoxOs. FoxOs are modulated at several mechanistic levels as indicated.