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. 2018 May 22;9(39):25474–25490. doi: 10.18632/oncotarget.25312

Table 4. Multivariate analysis of predictors for short TTR.

Location Colon cancer Rectal cancer
Stage Stage II Stage III Stage II Stage III
Factors HR
CI
P HR
CI
P HR
CI
P HR
CI
P
Gender: Male 0.73
0.53-1.02
NS
CEA: High 1.47
1.06-2.03
0.02 1.34
1.04-1.73
0.02
Nodal status: N2 1.23
0.92-1.64
NS
Lymphatic invasion
 ly2/3 1.83
1.03-3.05
0.04
 ly3 1.73
1.09-2.64
0.02 1.5
0.86-2.45
NS
Venous invasion
 v2/3 1.42
1.07-1.88
0.01
 v3 1.63
1.09-2.36
0.02
Type of recurrence:
 M1b 1.25
0.88-1.74
NS
Recurrence sites
 Liver (+) 1.44
0.99-2.09
NS 1.92
1.41-2.61
<0.0001
 Distant LN: (+) 1.53
0.84-2.61
NS 0.52
0.23-1.03
NS

CEA: Carcinoembryonic antigen, CI: confidence interval, HR: hazard ratio, LN: lymph node, NS: Not significant, TTR: time to recurrence.