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. 2018 May 22;9(39):25557–25571. doi: 10.18632/oncotarget.25374

Table 7. Gene Ontology (GO) analysis based on 15% differences of methylation level between groups (significant according to Benjamin adjusted p).

Group/Term N Genes* p, Benjamini
Cancer/Control
Pathways
 hsa04360: Axon Guidance 27 9.59E-06,.00261
 hsa05200: Pathways in Cancer 53 3.21E-04,.0429
 hsa04015: Rap1 Signaling Pathway 33 4.20E-04,.0375
 hsa04510: Focal Adhesion 32 6.40E-04,.0428
 hsa04724: Glutamatergic Synapse 21 8.63E-04,.046
Biological Process
 GO:0007156∼Homophilic Cell Adhesion via Plasma Membrane Adhesion Molecules 62 1.21E-27, 4.99E-24
 GO:0007165∼Signal Transduction 138 3.71E-07, 7.65E-04
 GO:0043547∼Positive Regulation of GTPase Activity 74 1.12E-05, .0153
 GO:0050885∼Neuromuscular Process Controlling Balance 14 3.22E-05, .0326
 GO:0007155∼Cell Adhesion 61 4.83E-05, .0391
 GO:0007399∼Nervous System Development 43 5.17E-05, .035
 GO:0016477∼Cell Migration 30 5.97E-05, .0346
Cellular Component
 GO:0005886∼Plasma Membrane 397 4.88E-08, 3.30E-05
Molecular Function
 GO:0005509∼Calcium Ion Binding 119 1.45E-15, 1.76E-12
Family/Control
Molecular Function
 GO:0005516∼Calmodulin Binding 28 3.88E-06,.00392
Obesity/Control
Biological Process
 GO:0007156∼Homophilic Cell Adhesion via Plasma Membrane Adhesion Molecules 32 1.04E-17, 2.30E-04
Cellular Component
 GO:0005886∼Plasma Membrane 158 3.61E-06,.0014
Molecular Function
 GO:0005509∼Calcium Ion Binding 51 3.60E-09, 2.29E-06

* Red fonts denote repeated components between the pairs of comparisons.