Table 2.
Results of practical hand wash test with murine norovirus according to EN1499
| Test parameter | Reference soft soap | PVP-I | CHG | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Product volume | Contact time (s) | Pre-value | Post-value | Log10 reductiona | Pre-value | Post value | Log10 reductiona | Pre-value | Post-value | Log10 reductiona |
| 3 mL | 15 | 5.46 | 4.22 | 1.24 | 5.66 | 4.09 | 1.57 | 5.52 | 4.62 | 0.90 |
| 30 | 6.33 | 4.71 | 1.62 | 6.41 | 4.28 | 2.13b | 6.04 | 4.87 | 1.18 | |
| 60 | 6.37 | 4.92 | 1.45 | 6.19 | 3.62 | 2.57b | 6.27 | 4.92 | 1.34 | |
| 5 mL | 15 | 6.28 | 4.88 | 1.41 | 6.61 | 4.62 | 1.99b | 6.58 | 5.30 | 1.28 |
| 30 | 5.99 | 4.64 | 1.35 | 6.05 | 4.28 | 1.78b | 5.90 | 4.82 | 1.08 | |
| 60 | 6.27 | 4.83 | 1.44 | 6.00 | 3.81 | 2.19b | 6.12 | 4.83 | 1.28 | |
Each value represents the mean from 30 samples (left and right hands of 15 volunteers)
CHG chlorhexidine gluconate 4% hand cleanser, PVP-I povidone-iodine 7.5% hand cleanser
aMean log10 reduction of post-washing versus pre-washing samples
bDemonstrated a significant difference versus the reference soft soap at the p = 0.01 level (one-sided) in the modified EN1499 test