Table 4.
Top 10 enriched KEGG pathways for UC_PPS. PValue: p-value from hypergeometric test; FDR: False Discovery Rate from Bonferroni Hypothesis.
| Geneset | Pathway description | Number of reference genes in the category | Number of genes in the user gene list and also in the category | Expected number in the category | Ratio of enrichment | PValue | FDR |
|---|---|---|---|---|---|---|---|
| hsa00020 | Citrate cycle (TCA cycle) - Homo sapiens (human) | 30 | 3 | 0.13 | 23.26 | 2.69E−04 | 0.06 |
| hsa04512 | ECM-receptor interaction - Homo sapiens (human) | 82 | 4 | 0.35 | 11.35 | 3.85E−04 | 0.06 |
| hsa04145 | Phagosome - Homo sapiens (human) | 154 | 4 | 0.66 | 6.04 | 4.00E−03 | 0.40 |
| hsa01200 | Carbon metabolism - Homo sapiens (human) | 114 | 3 | 0.49 | 6.12 | 1.25E−02 | 0.95 |
| hsa05144 | Malaria - Homo sapiens (human) | 49 | 2 | 0.21 | 9.50 | 1.85E−02 | 1.00 |
| hsa05130 | Pathogenic Escherichia coli infection - Homo sapiens (human) | 55 | 2 | 0.24 | 8.46 | 2.30E−02 | 1.00 |
| hsa00310 | Lysine degradation - Homo sapiens (human) | 59 | 2 | 0.25 | 7.89 | 2.63E−02 | 1.00 |
| hsa04920 | Adipocytokine signalling pathway - Homo sapiens (human) | 70 | 2 | 0.30 | 6.65 | 3.60E−02 | 1.00 |
| hsa03320 | PPAR signalling pathway - Homo sapiens (human) | 72 | 2 | 0.31 | 6.46 | 3.79E−02 | 1.00 |
| hsa04918 | Thyroid hormone synthesis - Homo sapiens (human) | 74 | 2 | 0.32 | 6.29 | 3.99E−02 | 1.00 |