Figure 3.

C9^−/− Mice Are Not Protected from EAU

Funduscopic EAU severity was analyzed after 24 days of EAU among normal, EAU, and C9^−/− EAU mice. Focal lesions, linear lesions, vasculitis, retinal hemorrhages, infiltrates, and retinal detachment were examined. According to the severity of these findings, the EAU clinical scores were graded on a scale of 0–4. (A) Fundus images from EAU and C9^−/− EAU group showing retinal inflammatory infiltrates (white arrowhead), vasculitis (white arrow), and retinal folds (black arrow). (B–F) Overall clinical score (B) and individual scores for vasculature (C), cellular infiltrations (D), optic disc (E), and structural damage (F). Values are represented as mean ± SEM.