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. 2018 Jun 4;9(6):675. doi: 10.1038/s41419-018-0591-0

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a GSEA plot suggested DDX39 expression positively correlated with metastasis associated gene signatures using TCGA data. b Western blot analysis of DDX39 levels after DDX39 overexpression in Huh1 and Hep3B. GAPDH was used as the loading control. c Wound healing assay of the effect of DDX39 overexpression on HCC cell migration. d Transwell assay of the effect of DDX39 overexpression on HCC cell invasion. e 3D spheroid invasion assay of the effect of DDX39 overexpression on HCC cell invasion. Data are shown as means ± SD. *p < 0.05