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. 2018 Jun 4;9(6):667. doi: 10.1038/s41419-018-0720-9

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a Human albumin level in the serum of LTH hu-mice at indicated time point after human FHC transplantation (n = 10; mean ± SEMs). b Immunohistochemically staining with anti-human Hep par1 (left) and anti-human CK8/18 (right) antibodies of liver tissues from LTH hu-mice 15 weeks after human FHC transplantation. H human hepatocytes, M mouse hepatocytes. Scale bar, 50 μm. c-e FCM analysis for the levels of human CD45⁺ lymphohematopoietic cells in PBMCs c and spleens d, and percentages of human CD3⁺CD4⁺ and CD3⁺CD8⁺ T cells, CD19⁺ B cells, and CD14⁺ monocytes/macrophages in the spleens e of TH hu-mice and LTH hu-mice at week 15 post-transplantation of human FTHY and CD34⁺ HSPCs. Data are presented as mean ± SEMs (n = 5 per group)