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. 2018 May 29;9:622. doi: 10.3389/fphys.2018.00622

Figure 3.

Figure 3

The “triple effect” or “triphasic effect.” Upon injection of Δ-9-THC (Siqueira et al., 1979) and anandamide (Varga et al., 1996) in urethane-anesthetized rats, an initial drop in blood pressure is followed by a short-lasting blood pressure peak mediated by vasoconstriction and then by delayed moderate and transient hypotension. Scheme adapted from the results of the aforementioned publications.