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. 2018 May 29;9:1097. doi: 10.3389/fimmu.2018.01097

Figure 7.

Figure 7

Final effect of dimethyl fumarate on B cell, non-follicular Th cells, and follicular cTfh cells subpopulations compared to healthy controls. (A–E) Percentages of naïve CD19+CD27−IgD+, transitional CD19+CD38highCD24high, plasmablasts CD19+CD38highCD24−, non-switched memory CD19+CD27+IgD+, and switched memory CD19+CD27+IgD− B cells from healthy controls (dark gray circles) and 12 months treated multiple sclerosis (MS) patients (12M: light gray circles). (F–I) Percentages of Th1, Th17, Th2, and Th17.1 non-follicular T cells and (J–M) percentages of cTfh1, cTfh17, cTfh2, and cTfh17.1 follicular T cells from healthy controls (dark gray circles) and 12 months treated MS patients (12M: light gray circles). Mann–Whitney U-test p-values: *p < 0.05, **p < 0.01, and ***p < 0.001.