Table 2.

Antifungal compounds derived from plants extracts showing activity against dermatophytes.

Plant	Phytochemical	Dermatophyte	MIC values	Reference
Thymbra capitata	EO, carvacrol (>65%)	5 dermatophyte strains	0.08–0.32 μL/mL	Salgueiro et al., 2004
Juniperus sp.	EO, α-pinene (>48%)	E. floccosum	0.08–2.5 μL/mL	Cavaleiro et al., 2006
		Trichophyton sp.
		Microsporum sp.
Lippia gracilis LGRA-106	EO, thymol (>61%)	T. rubrum	23.44–46.87 μL/mL	de Melo et al., 2013
Lippia gracilis LGRA-109	EO, carvacrol (>54%)	T. rubrum	46.87–93.75 μL/mL	de Melo et al., 2013
Thymus vulgaris	EO thymol (>48%)	Trichophyton sp.	NT∗	Sokovic et al., 2008
Vernonanthura tweedieana	sesquiterpene (6-cinnamoyloxy-1-hydroxyeudesm-4-en-3-one)	T. mentagrophytes M. gypseum	4–8 μg/mL	Portillo et al., 2005
Zuccagnia punctata	Chalcones	Trichophyton sp.	8–16 μg/mL	Svetaz et al., 2007
		M. gypseum
Glaucium oxylobum	Alkaloids	Trichophyton sp.	300 μg/mL	Morteza-Semnani et al., 2003
		Microsporum sp.
		E. floccosum
Tabernaemontana catharinensis	MMV alkaloid	T. rubrum	0.16 mg/mL	Medeiros et al., 2011
Baccharis darwinii	Diversinin (coumarin)	Trichophyton sp.	15.6 μg/mL	Kurdelas et al., 2010
		M. gypseum
Baccharis darwinii	Anisocoumarin H	Trichophyton sp.	62.5 μg/mL	Kurdelas et al., 2010
		M. gypseum
Lavandula viridis L’He′r	Monoterpenes	Trichophyton sp.	0.32–0.64 μL/mL	Zuzarte et al., 2011
		Microsporum sp.
		E. floccosum
Piper ecuadorense	Pinocembrin	Trichophyton sp.	125 μg/mL	Ramirez et al., 2013
Dorstenia barteri	Isobavachalcone	T. rubrum	1.2 μg/mL	Mbaveng et al., 2008
		M. audorium
Dorstenia barteri	Amentoflavone	T. rubrum	39.1 μg/mL	Mbaveng et al., 2008
Terminalia chebula	Apigenin	T. mentagrophytes	NT∗	Singh et al., 2014
Piper solmsianum	Orientin	Microsporum sp.	≤9 μg/mL)	De Campos et al., 2005
		Trichophyton sp.
		E. floccosum

^∗NT, MIC values non-tested, but antifungal activity evaluated through in vivo assays.