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. 2018 May 29;12:353. doi: 10.3389/fnins.2018.00353

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Copyright © 2018 Mohanty, Sinha, Remsik, Dodd, Young, Jacobson, McMillan, Thoma, Advani, Nair, Kang, Caldera, Edwards, Williams and Prabhakaran.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Methodology for single-participant analysis: (A) raw structural T1 scan (top) was preprocessed and spatially normalized to MNI space (bottom); (B) raw functional scan (top) was preprocessed up to smoothing (bottom); (C) smoothed fMRI was temporally filtered to obtain the low frequency oscillations within the range of 0.01–0.1 Hz using a bandpass filter; (D) 236 seeds comprising of 13 major brain networks were used to extract BOLD time courses at each seed region; (E) 236 × 236 rs-FC matrix was computed using the BOLD time courses; (F) unique pairwise correlations contained in the lower triangle of the rs-FC matrix were extracted and vectorized into a 27,730-dimensional vector.