Figure 1.

lncRNA CILA1 Was Remarkably Differentially Expressed in Cisplatin-Resistant TSCC Cells

(A) SCC9 cells were treated with cisplatin to establish chemoresistant cell lines, and the lncRNA differential expression profiles were analyzed by microarray. The mean fluorescence intensity was calculated and displayed as the average level. The results are presented as the lncRNA expression ratio of SCC9 chemoresistant versus the SCC9 parental cells. (B) Real-time qPCR was performed to examine the expression of the most remarkably upregulated lncRNAs in cisplatin-resistant cells compared with those in parental cells. (C) An MTS assay was performed to determine the cell viability of TSCC chemoresistant cells with knocked down lncRNA expression (**p versus mock < 0.01).