Table 3.

Dose of NAC intravenous and oral administration

Route of administration	Intravenous administration	Oral administration
Dose	Loading dose: 150mg/kg in 200ml of 5% dextrose (D5W) over 15 to 60 min. Second infusion: 50mg/kg in 500ml of D5W over 4 hours Third infusion: 100mg/kg in 1000ml of D5W over 16 hours	Loading dose: 140mg/kg Followed by 17 doses of 70mg/kg at 4-hour intervals (total duration of treatment, 72 hours).
Side effects	Nausea and vomiting	Anaphylactoid reactions manifested by rash, wheeze or mild hypotension