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. 2018 May 29;9:650. doi: 10.3389/fphys.2018.00650

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Copyright © 2018 Ioan, Gemble, Hamon, Schweitzer, Metche, Bonabel, Nguyen-Thi, Hascoet, Demoulin-Alexikova and Marchal.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) The MEF50 to FVC ratio is independent of FVC in children born at term (open symbols, p > 0.1), but is negatively correlated to FVC in those born extremely preterm (closed symbols, p < 0.005). (B) MEF50/FVC divided by the estimated elastic recoil pressure at corresponding volume (Pel,L₅₀) shows relationships to FVC similar to (A), with similar differences between controls and patients (only non-distended children are taken into account, see section “Discussion”).