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. 2018 May 14;25(7):R421–R434. doi: 10.1530/ERC-17-0309

Table 1.

Clinical trials involving the use of Anakinra and Ilaris for the treatment of different cancer types.

Treatment Cancer type Clinical trial identifier Clinical trial phase
Anakinra and standard of care Metastatic breast cancer Nbib1802970 Phase I
Anakinra and Bevacizumab Metastatic colorectal cancer Nbib2090101 Phase II
Gemcitabine, Nab-Paclitaxel, Cisplatin and Anakinra Pancreatic adenocarcinoma Nbib2550327 Early Phase I
Anakinra alone or with Dexamethasone Multiple myeloma Nbib635154 Phase II
Plasma cell neoplasm
Anakinra or Denosumab and Everolimus Advanced cancers Nbib1624766 Phase I
Lenalidomide and Dexamethasone with or without Anakinra Indolent plasma cell myeloma Nbib2492750 Phase I, followed by Phase II
Plasma cell myeloma
Smoldering plasma cell myeloma
PDR001 in combination with CJM112, EGF816, Ilaris (Canakinumab) or Mekinist (Trametinib) Colorectal cancer, triple-negative breast cancer, NSCLC, adenocarcinoma Nbib2900664 Phase I