Figure 2.
Sagittal (a) and coronal (b,c) T2-weighted HASTE magnetic resonance imaging (MRI) at 32 weeks’ gestation and axial two-dimensional ultrasound (2D-US) at 30+6weeks (d) in a fetus with a congenital anomaly (Case 113). (a–c) Fetal MRI shows reduced proportionality of the brain compared with the face, consistent with microcephaly. The cortex is smooth for gestational age, consistent with lissencephaly. A central skull defect with protrusion of brain tissue (arrow in b) is seen, consistent with a vertex cephalocele. Both fetal MRI (c) and 2D-US (d) fail to recognize the interhemispheric fusion between posterior frontal and anterior parietal lobes, consistent with syntelencephaly. Arrows in (c) and (d) identify midline fusion of the choroid plexuses.