Table 4.
Demographic and clinical factors after SBP in 95 patients predicting one-year mortality using Cox-regression analysis.
| Univariate |
Multivariate |
|||||
|---|---|---|---|---|---|---|
| HR | 95% CI | p value | HR | 95% CI | p value | |
| Gender | <0.001 | |||||
| Female (ref.) | 1 | |||||
| Male | 0.424 | 0.263–0.682 | ||||
| Age (per year) | 0.999 | 0.981–1.017 | 0.911 | |||
| Etiology | 0.206 | |||||
| Alcohol (ref.) | 1 | |||||
| Viral | 0.841 | 0.444–1.596 | ||||
| Autoimmune | 1.545 | 0.836–2.858 | ||||
| Other | 0.837 | 0.431–1.625 | ||||
| Acquisition SBP | 0.078 | |||||
| Community (ref.) | 1 | |||||
| Nosocomial | 1.761 | 0.938–3.303 | ||||
| Positive microbial ascites culture | 1.406 | 0.886–2.231 | 0.148 | |||
| Causative microorganism type | 0.561 | |||||
| Gram-negative bacteria (ref.) | 1 | |||||
| Gram-positive bacteria | 0.764 | 0.359–1.625 | ||||
| Yeast | 1.511 | 0.444–5.146 | ||||
| Multidrug-resistant microorganism | 1.989 | 0.972–4.073 | 0.060 | |||
| Antibiotic prophylaxis | 0.662 | 0.286–1.531 | 0.335 | |||
| Immunosuppressant use | 0.508 | 0.260–0.992 | 0.047 | |||
| HCC | 0.971 | 0.465–2.026 | 0.937 | |||
| MELD score (per point) | 1.060 | 1.030–1.091 | <0.001 | 1.060 | 1.030–1.091 | <0.001 |
| Albumin in serum (per point) | 0.967 | 0.927–1.008 | 0.109 | |||
| Platelets in serum (<150 ×109/l) | 2.179 | 1.226–3.870 | 0.008 | |||
| Low protein in ascites (<15 g/l) | 1.287 | 0.530–3.124 | 0.578 | |||
SBP: spontaneous bacterial peritonitis; MELD: model for end-stage liver disease; HCC: hepatocellular carcinoma; HR: hazard ratio; CI: confidence interval. Significant p values in univariable analysis (<0.100) and in multivariable analysis (<0.050) are highlighted in boldface.