Table 2.

Aberrant miRNAs associated with the cell cycle and apoptosis.

MicroRNAs	Type of deregulation	Target	Reference
miR-199a/b-3p	Downregulated	Cyclin D1	[15]
miR-302b	Downregulated	EGFR, Cyclin A, Cyclin D1, CDK2	[16, 17]
miR-184	Upregulated	SOX7	[18]
miR-200a	Downregulated	CDK6	[19]
miR-19a	Downregulated	Cyclin D1	[20]
miR125a-5p, miR-125b	Downregulated	sirtuin7, SUV39H1	[21, 22]
miR-140	Downregulated	TGFBR1, FGF9	[23]
miR-497, miR-195	Upregulated	CCNE1, CDC25A, CCND3, CDK4,	[24]
miR-451	Downregulated	cyclin D1, c-Myc	[25]
miR-517a, miR-17c	Upregulated	Pyk2	[26]
miR-371-5p	Downregulated	PRPF4B	[27]
miR-221, miR-1228	Upregulated	p53	[28, 29]
miR-1269	Upregulated	FOXO1	[30]
miR-148a	Upregulated	PTEN	[31]
miR-1228	Upregulated	p53	[32]
miR-138	Upregulated	Cyclin D3	[33]
miR-141	Downregulated	HNF-3beta	[34]
miR-24	Upregulated	SOX7	[35]
miR-133a	Upregulated	AKT, ERK	[36]
miR-129-5p	Downregulated	VCP	[37]
miR-122	Upregulated	Galpha12	[38, 39]
miR-93	Upregulated	PTEN, CDKN1A	[40]
miR-105	Upregulated	AKT1	[41]
miR-125b	Upregulated	Bcl-w, IL6R	[42]
miR-34a	Upregulated	UFC1	[43]
miR-383	Downregulated	APRIL	[44]
miR-221	Downregulated	Bmf	[45]