Table 1.
TCM ingredients’ AD-matched list in PubMed.
| No. | Frequency | TCM ingredients | PubChem ID | Origin ontology in HMDB |
|---|---|---|---|---|
| 1 | 41288 | Tau | 156615 | Endogenous |
| 2 | 5431 | Glutamate | 5128032 | Bacteria and beans |
| 3 | 3609 | Cholinesterase | 4460501 | Not available |
| 4 | 3557 | Acetylcholine | 5315629 | Endogenous |
| 5 | 3453 | Dopamine | 681 | Endogenous |
| 6 | 2824 | Choline | 305 | Many plants and animal organs |
| 7 | 1999 | Nicotine | 89594 | Tobacco |
| 8 | 1973 | Melatonin | 896 | Endogenous |
| 9 | 1898 | Glutathione | 124886 | Drug metabolite and Endogenous |
| 10 | 1722 | Aspartate | 5460541 | Endogenous |
| 11 | 1718 | Serotonin | 5202 | Endogenous |
| 12 | 1593 | Tyrosine | 6057 | Endogenous |
| 13 | 1534 | Scopolamine | 5184 | Solanaceae |
| 14 | 1432 | Serine | 5951 | Endogenous |
| 15 | 1372 | Curcumin | 969516 | Curcuma longa |
| 16 | 1089 | Levodopa | 6047 | Endogenous |
| 17 | 939 | Estradiol | 5757 | Drug, Endogenous, Food |
| 18 | 931 | Methionine | 6137 | Drug metabolite and Food |
| 19 | 788 | Creatine | 586 | Endogenous |
| 20 | 785 | Physostigmine | 5983 | Drug |
TCM, traditional Chinese medicine; HMDB, human metabolome database.