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. 2018 Jun 4;18:626. doi: 10.1186/s12885-018-4518-z

Table 2.

Histopathological and immunohistochemical characteristics in control and indole-3-carbinol (I3C) xenograft groups

Control xenograft (%) I3C xenograft (%) p-value
Ulceration 33.3 0.0 p = 0.028
Sebaceous hyperplasia 8.3 83.3 p < 0.001
Dermal emboli 0.0 41.7 p = 0.012
Tumor emboli (non-dermal) 16.7 58.3 p = 0.035
Degenerated emboli 0.0 8.3 p > 0.05
Thrombosis 33.3 0.0 p = 0.036
Lipid-rich subpopulation 0.0 66.7 p = 0.001
Distant metastases (any location) 8.3 33.3 p > 0.05
Liver metastases 0.0 33.3 p = 0.028
Control xenograft (%, mean ± standard deviation) I3C xenograft (%, mean ± standard deviation) p-value
Ki-67 index 62.2 ± 4.55 54.5 ± 3.79 p < 0.001
Caspase index 6.9 ± 1.35 27.5 ± 2.33 p < 0.001

P values in boldface are significant. These values are p < 0.05

HHS Vulnerability Disclosure