Table 2.
Histopathological and immunohistochemical characteristics in control and indole-3-carbinol (I3C) xenograft groups
Control xenograft (%) | I3C xenograft (%) | p-value | |
---|---|---|---|
Ulceration | 33.3 | 0.0 | p = 0.028 |
Sebaceous hyperplasia | 8.3 | 83.3 | p < 0.001 |
Dermal emboli | 0.0 | 41.7 | p = 0.012 |
Tumor emboli (non-dermal) | 16.7 | 58.3 | p = 0.035 |
Degenerated emboli | 0.0 | 8.3 | p > 0.05 |
Thrombosis | 33.3 | 0.0 | p = 0.036 |
Lipid-rich subpopulation | 0.0 | 66.7 | p = 0.001 |
Distant metastases (any location) | 8.3 | 33.3 | p > 0.05 |
Liver metastases | 0.0 | 33.3 | p = 0.028 |
Control xenograft (%, mean ± standard deviation) | I3C xenograft (%, mean ± standard deviation) | p-value | |
Ki-67 index | 62.2 ± 4.55 | 54.5 ± 3.79 | p < 0.001 |
Caspase index | 6.9 ± 1.35 | 27.5 ± 2.33 | p < 0.001 |
P values in boldface are significant. These values are p < 0.05