Table 2.

Five prevalent themes influencing AYA decision making were identified in ≥90% of participants

Theme Classification	Theme	Example
Positive	Severity of illness/urgency (95%)	“I brought up side effects a few times, but if there weren’t really any options or the current options weren’t working and my team was at a loss of what to do. I don’t see that I would have a choice.”
Negative	Concern about side effects (90%)	“Yes, it would. Permanent side effects? No thanks. The side effects I’ve already been having with chemo are harsh enough... definitely side effects would be huge thing”
Neutral	Recruitment method (100%)	“I was approached very nicely and academically and they gave me the right information. I was able to meet a lot of different professionals working on the trial and felt confident because I got a lot of different perspectives by different teams.”
	Additional information (95%)	“I like that I was able to talk about it with my doctor… I know ultimately I make most of the decisions for myself but I hold him in very high regard.”
	Opinion of others (100%)	“My friends and family are very informed and aware of what is going on with me. Always want to come to the hospital and they all do their own research…It’s great, I am very supported.”