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. 2018 Jun 5;19:438. doi: 10.1186/s12864-018-4818-3

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Heatmap of significant probes that exhibit differences in methylation state and direction in different tissues. A small number of loci show differences in the direction of change in methylation in different embryonic regions ED = embryonic disc, TP = trophectoderm peripheral, TE = trophectoderm adjacent to embryonic disc, SOV = superovulation-derived embryo, IVP = in vitro-derived embryo. The ID of each probe is outlined on the right hand side of the map and their genomic location can be found at http://emb-bioinfo.fsaa.ulaval.ca/bioinfo/html/index.html