Table 1.
Subject characteristics, basal and postprandial FGF19 serum concentrations
| Variables | Control | Overweight | Obesity | p-value |
|---|---|---|---|---|
| N (men/women) | 16 (7/9) | 14 (8/6) | 12 (6/6) | n.s.a |
| Age (years) | 29.5 (24.0–53.0) | 49.0 (38.8–57.3) | 48.0 (37.0–57.3) | 0.551b |
| BMI (kg/m2) | 24.2 (21.8–26.6) | 28.3 (26.3–29.2) | 35.3 (32.7–39.0) | < 0.001b |
| FGF19 (pg/ml) | ||||
| t = 0 h | 178.5 (101.0–257.0)c | 127.5 (70.0–161.3) | 116.0 (51.0–134.3)c | 0.01c |
| t = 2 h | 244.5 (161.5–377.5)c | 163.0 (78.5–168.3)c | 181.0 (85.3–393.0) | 0.004c |
| t = 4 h | 332.5 (202.0–590.8) | 207.0 (112.5–365.0) | 220.0 (138.8–385.3) | 0.445b |
| t = 6 h | 211.0 (165.3–296.3) | 154.0 (124.0–254.0) | 184.5 (110.5–274.3) | 0.445b |
All data are given as median (interquartile range)
aChi-square-test
bKruskal-Wallis-test
cMann-Whitney-U-test