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. 2018 Jun 4;15:174. doi: 10.1186/s12974-018-1212-7

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Different morphology of microglia and macrophages at day 14 after ischemic stroke. Representative photomicrographs with subsequent magnified images represent different morphology of microglia/macrophages in a intact contralateral hemisphere, b border of the ischemic lesion of ipsilateral hemisphere, and c the core of the ischemic lesion of ipsilateral hemisphere. eGFP⁺ microglia display at least three distinct phenotypes at day 14 after stroke including ramified cells (top row), intermediate cells (middle row), and amoeboid cells (bottom row). RFP⁺ macrophages show oval or round shape without apparent processes. F4/80⁺ cells, alternatively activated cells, display intermediate and amoeboid shape. Scale bar 50 μm