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. 2018 Jun 4;19:432. doi: 10.1186/s12864-018-4810-y

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Expression profiling of the CCHCR1-HEK293 cell lines highlighted cell adhesion and actin cytoskeleton. a Heatmaps showing gene expression of focal adhesion and regulation of actin cytoskeleton in the CCHCR1 Iso1Non-risk (1 N), Iso1Risk (1R), Iso3Non-risk (3 N), and Iso3Risk (3R) cell lines, and in the vector transfected cells (V), and wild type HEK293 (WT). Color key: red represents upregulated and blue downregulated expression (row Z-score). b The expression of FN1, TLN1, and SYT1 in the CCHCR1-HEK293 cell lines was validated with qPCR, and compared with the gene expression in the wild type cells. Error bars: standard deviation. Here shown normalization with HPRT1