Table 4.
Univariate and multivariate analyses for determinants of overall survival
| Parameters | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| P value | Hazard ratio | 95% CI | P value | |
| Age (< 65/≥65 years) | 0.304 | |||
| Gender (Male/Female) | 0.325 | |||
| ECOG performance status (0/1) | 0.187 | |||
| Platelet count (< 14.9 × 104/> 14.9 × 104 /μL) | 0.07 | |||
| Child-Pugh score (A/B) | 0.008 | |||
| Diameter of main tumor(< 80 mm/≥ 80 mm) | 0.036 | |||
| Macroscopic vascular invasion (without/with) | 0.646 | |||
| TACE refractory (without/with) | 0.101 | |||
| AFP (< 1895/≥ 1895 ng /mL) | 0.515 | |||
| DCP (< 3854/≥ 3854 mAU/mL) | 0.055 | |||
| Extrahepatic spread (without/with) | 0.004 | 3.905 | 1.420–10.736 | 0.008 |
Abbreviations: AFP alpha-fetoprotein, DCP des-gamma-carboxy prothrombin, ECOG Eastern Cooperative Oncology Group, MVI macroscopic vascular invasion, TACE transarterial chemoembolization