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. 2018 Jun 5;131(11):1349–1356. doi: 10.4103/0366-6999.232814

Supplemental File 1.

MOOSE checklist

Item number Recommendation Reported on page number
Reporting of background should include

1 Problem definition 2
2 Hypothesis statement 2
3 Description of study outcome(s) 2
4 Type of exposure or intervention used None
5 Type of study designs used 2
6 Study population 2

Reporting of search strategy should include

7 Qualifications of searchers (e.g., librarians and investigators) 3
8 Search strategy, including time period included in the synthesis and keywords 3
9 Effort to include groups available studies, including contact with authors 3
10 Databases and registries searched 2
11 Search software used, name and version, including special features used (e.g., explosion) 2
12 Use of hand searching (e.g., reference lists of obtained articles) None
13 List of citations located and those excluded, including justification 3,4
14 Method of addressing articles published in languages other than English None
15 Method of handling abstracts and unpublished studies 2
16 Description of any contact with authors None

Reporting of methods should include

17 Description of relevance or appropriateness of studies assembled for assessing the hypothesis to be tested 3
18 Rationale for the selection and coding of data (e.g., sound clinical principles or convenience) None
19 Documentation of how data were classified and coded (e.g., multiple raters, blinding, and interrater reliability) None
20 Assessment of confounding (e.g., comparability of cases and controls in studies where appropriate) 3
21 Assessment of study quality, including blinding of quality assessors, stratification or regression on possible predictors of study results 3
22 Assessment of heterogeneity 3
23 Description of statistical methods (e.g., complete description of fixed or random effects models, justification of whether the chosen models account for predictors of study results, dose-response models, or cumulative meta-analysis) in sufficient detail to be replicated 3
24 Provision of appropriate tables and graphs 3

Reporting of results should include

25 Graphs summarizing individual study estimates and overgroups estimate 3
26 Table giving descriptive information for each study included 4
27 Results of sensitivity testing (e.g., subgroup analysis) 4,5
28 Indication of statistical uncertainty of findings None

Reporting of discussion should include

29 Quantitative assessment of bias (e.g., publication bias) 7
30 Justification for exclusion (e.g., exclusion of non-English language citations) None
31 Assessment of quality of included studies 7

Reporting of conclusions should include

32 Consideration of alternative explanations for observed results 7
33 Generalization of the conclusions (i.e., appropriate for the data presented and within the domain of the literature review) 7
34 Guidelines for future research 7
35 Disclosure of funding source None

MOOSE: Meta-Analysis of Observational Studies in Epidemiology.