Table 4.
Characteristics of the chronic hepatitis B patients from the hepatology and community gastroenterology and primary care clinics of the San Francisco Bay area consortium
| Parameters | Results |
|---|---|
| Total number, N | 2000 |
| Male | 1117 (55.8%) |
| Age | 43 (18–88) |
| HBeAg-positive | 444 (22.2%) |
| Active HBeAg-positive (non cirrhotic)* | 272 (14%) |
| Active HBeAg-negative (non cirrhotic)* | 510 (26%) |
| ALT (U/L) | 39 (3–2809) |
| HBV DNA (log10 IU/mL) | 4.0 (1.3–11.3) |
| Cirrhosis | 185 (9%) |
*Active is defined by an elevation of ALT > 2× upper limit of normal or evidence of significant histological disease plus elevated HBV DNA above 2000 IU/mL for HBeAg-negative, and above 20,000 IU/mL for HBeAg-positive [6]
HBeAg hepatitis B e antigen, ALT alanine aminotransferase