Table III.
Top 20 differentially expressed genes in osteoarthritis
| ID | Symbol | Combined effect size | p-value | False discovery rates | Up/down |
|---|---|---|---|---|---|
| 4616 | GADD45B | -2.30652 | 1.33E-15 | 1.42E-11 | Down |
| 55002 | TMCO3 | 1.860201 | 7.15E-14 | 3.82E-10 | Up |
| 5742 | PTGS1 | 1.772798 | 4.88E-13 | 1.74E-09 | Up |
| 53346 | TM6SF1 | 1.732943 | 1.14E-12 | 3.05E-09 | Up |
| 2355 | FOSL2 | -2.05783 | 5.63E-12 | 6.09E-09 | Down |
| 57018 | CCNL1 | -1.78228 | 5.71E-12 | 6.09E-09 | Down |
| 10560 | SLC19A2 | -2.1303 | 1.46E-11 | 1.20E-08 | Down |
| 64854 | USP46 | 1.671456 | 1.39E-11 | 1.20E-08 | Up |
| 2289 | FKBP5 | -1.65731 | 2.25E-11 | 1.60E-08 | Down |
| 1519 | CTSO | 1.590246 | 3.16E-11 | 2.11E-08 | Up |
| 25834 | MGAT4C | 1.652285 | 4.54E-11 | 2.85E-08 | Up |
| 29071 | C1GALT1C1 | 1.577996 | 4.91E-11 | 2.91E-08 | Up |
| 10797 | MTHFD2 | -1.68311 | 7.96E-11 | 4.09E-08 | Down |
| 79862 | ZNF669 | -1.54828 | 7.77E-11 | 4.09E-08 | Down |
| 25976 | TIPARP | -1.8764 | 1.02E-10 | 4.93E-08 | Down |
| 7538 | ZFP36 | -1.74104 | 1.11E-10 | 5.17E-08 | Down |
| 2628 | GATM | 1.510396 | 4.21E-10 | 1.73E-07 | Up |
| 23090 | ZNF423 | 1.489729 | 5.19E-10 | 1.85E-07 | Up |
| 2872 | MKNK2 | -1.44317 | 5.09E-10 | 1.85E-07 | Down |
| 54504 | CPVL | 1.439288 | 5.17E-10 | 1.85E-07 | Up |