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. 2018 May 5;7(4):289–297. doi: 10.1302/2046-3758.74.BJR-2017-0302.R1

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© 2018 Author(s) et al.

This is an open-access article distributed under the terms of the Creative Commons Attributions licence (CC-BY-NC), which permits unrestricted use, distribution, and reproduction in any medium, but not for commercial gain, provided the original author and source are credited.

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graphic file with name bonejointres-07-289-g005.jpg — Flow cytometry showing C-X-C chemokine receptor type 4 (CXCR-4) surface expression in mesenchymal stem cells (MSCs) labelled with anti-CXCR-4 antibody, from a) young, b) adult control, and c) ovariectomized (OVX) rats. Young MSCs have the highest expression of CXCR-4 (87%), followed by MSCs from adult control (32%); MSCs from OVX rats (19%) had the lowest expression of CXCR-4 (n = 3). In a), the red histogram shows the secondary background control and the green histogram shows the CXCR-4 expression in young MSCs. In figures b) and c), the green histogram demonstrates the background expression and the red histogram shows the CXCR-4 expression. FITC, fluorescein isothiocyanate.