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. 2018 May 29;9:1110. doi: 10.3389/fmicb.2018.01110

Table 1.

Annotation of the top ten HVPC clusters.

SEED SEED
Cluster Size nr Pfam FIGfams pVOG GO subsystem category
1 72340 MULTISPECIES: class A broad-spectrum beta-lactamase TEM-116 [Bacteria] Beta-lactamase Beta-lactamase (EC 3.5.2.6) Virulence, Resistance to antibiotics and toxic compounds
2 27442 ORF1 [Torque teno virus] TT viral orf 1
3 21304 ORF1 [Torque teno virus] TT viral orf 1
4 12799 orf00052, partial [uncultured crAssphage]
5 12425 putative helicase [Lactococcus phage 1706] Bbp29; D5-like protein; DNA primase; DNA primase/helicase; DNA primase/polymerase; P4 family phage/plasmid primase; gp108; gp109; gp11; gp34; gp49; gp60; gp68; gp69; gp70; gp71; gp72; gp74; gp81; gp86; gp88; gp89; gp90; gp92; gp94; gp9a; helicase; hypothetical protein; orf40; phage associated primase; phage associated primase/P4 family phage/plasmid primase; phage-associated primase/P4 family phage/plasmid primase; primase; primase/polymerase; putative DNA primase; putative DNA-polymerase or DNA-primase; putative P4 family primase; putative predicted product; putative primase; putative primase/helicase protein
6 11731
7 9611 ORF1 [Torque teno virus] TT viral orf 1
8 8814
9 7169 beta-galactosidase alpha-peptide [unidentified cloning vector]
10 6489 phage tail protein [[Clostridium] symbiosum] DNA-binding domain protein; HTH DNA binding domain protein; gp106; hypothetical protein; structural protein

nr, NCBI’s non-redundant protein database; pVOG, prokaryotic virus orthologous groups; GO, gene ontology; TT, Torque Teno Virus. Cluster size refers to the number of ORFs in each cluster.