Table 1. Anti–β1 integrin mAbs.

Clone	Species	Epitope	Conformational specificity	Function	Classification	References
K20	Mouse	EGF-like repeats	Pan	-	Total	Amiot et al. (1986); Takada and Puzon (1993)
9EG7	Rat	EGF-like repeats	Extended; LIBSa	Activating	Active	Lenter et al. (1993); Bazzoni et al. (1995); Su et al. (2016)
12G10	Mouse	βA domain	Open headpiece; LIBS	Activating	Active	Mould et al. (1995, 1996,Su et al. (2016)
Huts-4	Mouse	Hybrid domain	Open headpiece; LIBS	Activating	Active	Luque et al. (1996); Su et al. (2016)
mAb13	Rat	βA domain	Closed headpiece; LABS	Inhibitory	Inactive	Akiyama et al. (1989); Mould et al. (1996); Su et al. (2016)
AIIB2	Rat	βA domain	LABS	Inhibitory	Inactive	Fig. S1; Werb et al. (1989); Takada and Puzon (1993); Park et al. (2008)

We defined β1 integrin subpopulations labeled by different mAbs as total, active, and inactive as described in Materials and methods. All mAbs defined as active in this study label the same subpopulation as seen by a maximal colocalization (Fig. 3).

^aLigand-induced binding site.