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. 2018 Jun 4;217(6):2167–2184. doi: 10.1083/jcb.201708053

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© 2018 Isensee et al.

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Figure 9. — Phosphatase activity decreases dissociation of PKA-II at baseline and after stimulation. The effect of increasing phosphatase activity on the internal states of the best model after stimulation with Fsk or PGI₂ is shown. Different colors indicate phosphatase activities ranging from a 100-fold reduction (blue lines) to a 100-fold increase (red lines) compared with the estimated phosphatase activity (green lines).