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Evaluation of permeability of Mel across Caco-2 epithelial cell layers treated with Mel and optimized Mel PVA formulations for 1 h.
Notes: Values are presented as mean±SD, n=4. Statistical analysis: ANOVA followed by Bonferroni posttest. Statistically significant differences are: ***p<0.001, compared to control group; ###p<0.001 compared to the indicated columns.
Abbreviations: Mel, meloxicam; PVA, poly(vinyl alcohol); Papp, apparent permeability coefficients.
