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. 2018 May 31;11:3257–3265. doi: 10.2147/OTT.S165000

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© 2018 Xie et al. This work is published and licensed by Dove Medical Press Limited

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Apa-MS but Apa-Sol inhibited the EMT of HCC cells induced by RFA at mRNA level. Tumors from solvent control group, RFA group, Apa-Sol group, Apa-MS group, RFA + Apa-Sol group and RFA + Apa-MS group were harvested, and total mRNA was extracted. The relative mRNA level of (A) E-cadherin, (B) N-cadherin and (C) vimentin is shown as mean ± SD. *P<0.05.

Abbreviations: Apa-MS, apatinib microcrystal formulation; Apa-Sol, apatinib solution; EMT, epithelial–mesenchymal transition; HCC, hepatocellular carcinoma; RFA, radiofrequency ablation.