Table 2.

Pre-screening failures according to genetic status and gender

Criteria	Main reason	Carriers (n=233)	Non-carriers (n=67)	p-value	Female (n=162)	Male (n=138)	p-value
I19	Expected inability to comply with visit schedule, n, %	82(35.0%)	36(53.7%)	0.007	65(40.1%)	53(38.4%)	0.81
I8	Criterion MCI, n, %	34(14.6%)	5 (7.5%)	0.15	22(13.5%)	17(12.3%)	0.86
E1	Not in good health, n, %	28(12.0%)	11(16.4%)	0.40	21(12.9%)	18(13.0%)	1.00
E18	Substance dependence, n, %	20 (8.6%)	5 (7.5%)	1.0	3 (1.9%)	22(15.9%)	p<0.0001
I14	Learning/comprehension difficulties or illiteracy, n, %	21 (9%)	1 (1.5%)	0.035	11 (6.8%)	11 (7.9%)	0.82

Note. n = number, I-inclusion, E-exclusion; Comparisons performed with Fisher’s exact test; Bold values denote p-value <0.05