The morphological dose-response to mating pheromone represented by the cellular formation of a mating projection (i.e., shmoo) was quantified as a percentage of total cells in a population by DIC microscopy. Data were fit to a sigmodal dose-response curve with variable slope.
(A) Effect of individual Ste18Nt phosphorylation mutations on the mating response.
(B) Effect of Ste18Nt phosphorylation mutations in strains exclusively expressing the Fus3 non-docking mutant Ste5ND.
Error bars represent SEM across ≥200 cells per experiment.
See also Table S3.