Fig. 1.

Visualization of alterations in resting-state connectivity induced by a medium sized brain tumor in the striatum. (a) Radar plot showing changes in resting-state connectivity between the right (i.e. ipsilateral) hippocampus and other ROI for a normal (gray) and medium-sized (tumor volume = 24.42 mm³) tumor-bearing (red) brain. (b) Healthy brain label field overlaid over an anatomical image, showing contralateral hippocampus (orange arrow), ipsilateral hippocampus (white arrow), contralateral neocortex (dark blue – left), ipsilateral neocortex (green – right), and brainstem (green – bottom). (c) Ipsilateral hippocampus resting-state connectivity map overlaid on an anatomic image for a normal brain. (d) Tumor-bearing label field overlaid on an anatomical image showing tumor (red with white “T”), contralateral hippocampus (orange arrow), ipsilateral hippocampus (white arrow), contralateral neocortex (dark blue - left), and ipsilateral neocortex (green). (e) Ipsilateral neocortex resting-state connectivity map overlaid on an anatomical slice for a tumor-bearing brain. Tumor location is indicated by white hatched outline in (e). Head orientation (L = left, R = right, D = dorsal, V = ventral) indicated in the upper left corner of panels (b) and (d). Resting-state connectivity map overlays were thresholded at p < 0.05 with the Bonferonni correction. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)